Endocrine Abstracts

Objectives: Some hypothyroid patients are critical of their care, although this appears to vary between countries. The quality of thyroid care delivered, and the perceived patient experience may be influenced by characteristics of specialists such as age, sex, experience, and workplace setting. Here, we aimed to explore geographical differences in thyroid specialist characteristics.Methods: THESIS is a large European questionnaire survey of thyroid speci...

Objectives: Glucocorticoids (GCs) are the first line therapy in moderate to severe, active thyroid eye disease (TED). While their beneficial immunosuppressive effects are well known, direct connective tissue effects are less characterized. The accumulation of extracellular matrix component hyaluronan (HA) and increased proliferation rate of fibroblasts are hallmarks connective tissue changes in TED. We examined the effect of methylprednisolone (MP), prednisolone (P), hydrocort...

Objectives: We present findings from the UK arm of the THESIS collaboration, a pan-European survey of endocrinologists’ opinions and current practice in the management of hypothyroid and euthyroid disorders.Methods: UK clinical members of the Society of Endocrinology and the British Thyroid Association were invited to participate in an online survey.Results: 272 of 1295 (21%) eligible members completed the survey. More than 50...

BackgroundHypothyroidism due to autoimmune thyroiditis (AITD) leads to atherogenic lipid profile and therefore might increase the cardiovascular risk of patients. Fetuin-A is a hepatokine with a role in the regulation of mineralization, metabolism and the cardiovascular system. Fetuin-A levels are known increased in obesity-linked diseases. To date, the role of fetuin-A in autoimmune thyroiditis has not been thoroughly investigated.<p class="abstext"...